Revolutionize Your Protein Quantification Approach
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Applications
PICO enables groundbreaking applications in the areas of:
- Highly-sensitive protein biomarker detection
- Signaling pathway activity analysis
- Disruptive cancer research applications
- Innovative assays for pharmaceutical research
- Extracellular vesicle (EV) analysis

Performance
The PICO Products are based on an immunoassay concept that utilizes digital PCR (dPCR) technology for readout. This unique approach results in the following powerful features and benefits:
- True absolute quantification of protein targets - no need for external reference
- Multiplex and high-throughput analysis - detect up to 96 samples simultaneously
- Small input sample requirement (down to 1 µL) - save on precious samples
- Femtomolar sensitivity - detect the undetectable targets
- Homogeneous, wash-free workflow - no loss of material
Upcoming events
Meet us in person and learn about the power of PICO at the following conferences:

Use-cases
The PICO technology expands the advantages of digital PCR into the world of proteins. PICO aims to replace traditional and cumbersome technologies such as western blot, co-immunoprecipitation (coIP), ELISA, by enalbing the true absolute quantification of protein targets without the need of a reference standard.
- Measure absolute amounts of your protein
- Convenient workflow
- Only one instrument required
- 200-fold sensitivity gain
- Read our application note
- Only 2 µL input material required
- No target enrichment required
- Wash-free workflow
- 200-fold sensitivity gain
- Read our application note
- Precise counting of EV vesicles in your sample
- Detecteion of both EV membrane and cargo proteins
- Read our application note
- Quantification of post-translational modifications
- splitPICO workflow for simultaneus quantification of up to 12 targets
PICO - The Absolute Protein Assay
Actome provides everything required for the absolute quantification of proteins, protein interactions, post-translational mopdifications, and extracellular vesicles (EVs).
- Sample volumes down to 1 µL
- Measurement in the native environment
- Use cells, tissue, or any liquid biological samples
- Quantify proteins, protein interactions and post-translational modifications
- Labeling of antibodies with PICOglue Labels
- Robust & highly efficient PICOglue labeling technology
Products:
- Digital assay with femtomolar sensitivtiy
- Wash-free workflow
- Zero background
Products:
- Compatible with QIAGEN's QIAcuity dPCR instrument
- Multiplexing: analyze up to 4 different PICOglue Labels simultaneously
- Online analysis software
- Personal cloud-based workspace
- Free registration
- Absolute quantification of targets
- Direct graphical output of data
- Basic statistical evaluation
PICO Kits & Services
Say hi to PICO and say bye to western blot, coIP, and ELISA!
PICO Kits>

The PICO Kits guide you through the entire PICO workflow from antibody labeling to running the PICO Assay on your dPCR device. The PICO Kits are your perfect choice for performing PICO Assays in your lab.
Buy the PICO Kits Ask for a quote Discover the PICO KitsPICO Services>

We offer a comprehensive range of services to help you utilize the PICO technology. The services range from antibody labeling and quality control to fully customised PICO Assay development. Reach out to us below to discuss your project!
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Join us in advancing science and technology with PICO, the Absolute Protein Assay. Reach out to us today!
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