Revolutionize Your Protein Quantification Approach

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Applications

Our PICO Kits, together with AMULATOR, our data analysis software, allow groundbreaking applications in the areas of:

Ultra-sensitive protein biomarker detection
Signaling pathway activity analysis
Disruptive cancer research applications
Innovative assays for pharmaceutical research
Extracellular vesicle (EV) analysis

Performance

The PICO Products are based on a digital immunoassay concept that utilizes digital PCR (dPCR) technology for readout. This unique approach results in the following powerful features and benefits:

Absolute quantification of protein targets - no need for external reference
Multiplex and high-throughput analysis - detect up to 96 samples simultaneously
Small input sample requirement (down to 0.5 µL) - save on precious samples
Femtomolar sensitivity - detect the undetectable targets
Homogeneous, wash-free workflow - no loss of material

Use-cases

The PICO technology expands the advantages of digital PCR into the world of proteins. PICO aims to replace traditional and cumbersome technologies such as western blot, co-immunoprecipitation (coIP), and ELISA, and allows the development of novel quantitative protein assays.

Superior sensitivity
Measure absolute amounts of your protein
More convenient workflow
Only one instrument required
Read our application note

Small input material required
Higher sensitivity
No target enrichment required
Wash-free workflow
Read our application note

Detection and quantification of extracellular vesicles (EVs)
Quantification of post-translational modifications
Multiplex approaches targeting several targets in parallel

Sample to Result

Actome, in collaboration with your preferred antibody supplier, provides everything required for a comprehensive analysis of your protein targets. Explore the PICO products offered in our webshop.

Sample volumes down to 1 µL
Measurement in the native environment
Use cells, tissue, or any liquid biological samples
Quantify proteins, protein interactions and post-translational modifications

Use your own monoclonal antibodies
Pre-labeled antibodies are also available

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Further information

Labeling of antibodies with PICOglue Labels
Robust & highly efficient PICOglue labeling technology

Products:

Further information

Digital assay with femtomolar sensitivtiy
Wash-free workflow
Zero background

Products:

Further information

Compatible with QIAGEN and Stilla dPCR instruments
Multiplexing: analyze up to 4 different PICOglue Labels simultaneously

Further information

Online analysis software
Personal cloud-based workspace
Free registration

Further information

Absolute quantification of targets
Direct graphical output of data
Basic statistical evaluation

PICO Products

Say hi to PICO and say bye to western blot/coIP/ELISA!

PICO Kits

The PICO Kits guide you through the entire PICO workflow from antibody labeling to running the PICO Assay on your dPCR device. The PICO Kits are your perfect choice for performing PICO Assays in your lab.

Buy the PICO Kits Ask for a quote Discover the PICO Kits

PICO Services

We offer a comprehensive range of services to help you utilize the PICO technology. The services range from antibody labeling and quality control to fully customised PICO Assay development. Reach out to us below to discuss your project!