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Revolutionize Your Protein Quantification Approach

Watch the full video Learn more about PICO

Applications

Our PICO Kits, together with AMULATOR, our data analysis software, allow groundbreaking applications in the areas of:

  • Ultra-sensitive protein biomarker detection
  • Cellular pathway analysis
  • Disruptive cancer research applications
  • Innovative assays for pharmaceutical research
  • Extracellular vesicle (EV) analysis

Performance

The PICO Products are based on a digital immunoassay concept that utilizes digital PCR (dPCR) technology for readout. This unique approach results in the following powerful features and benefits:

  • Absolute quantification of protein targets - no need for external reference
  • Multiplex and high-throughput analysis - detect up to 96 samples simultaneously
  • Small input sample requirement (down to 0.5 µL) - save on precious samples
  • Femtomolar sensitivity - detect the undetectable targets
  • Homogeneous, wash-free workflow - no loss of material 

Use-cases

The PICO technology expands the advantages of digital PCR into the world of proteins. PICO aims to replace traditional technologies such as western blot, co-immunoprecipitation (coIP), and ELISA, and allows the development of novel quantitative protein assays

  • Superior sensitivity
  • Measure absolute amounts of your protein
  • More convenient workflow
  • Only one instrument required
  • Read our application note

  • Small input material required
  • Higher sensitivity
  • No target enrichment required
  • Wash-free workflow
  • Read our application note

Sample to Result

Actome, in collaboration with your preferred antibody supplier, provides everything required for a comprehensive analysis of your targets. Explore the PICO products offered in our webshop.

  • Sample volumes down to 1 µL
  • Measurement in the native environment
  • Use cells, tissue, or any liquid biological samples
  • Quantify proteins, protein interactions and post-translational modifications
Antibodies
  • Use your own monoclonal antibodies
  • Pre-labeled antibodies are also available

Products:

Labeling
  • Labeling of antibodies with PICOglue Labels
  • Robust & highly efficient PICOglue labeling technology

Products:

PICO
  • Digital assay with femtomolar sensitivtiy
  • Wash-free workflow
  • Zero background

Products:

dPCR
  • Compatible with QIAGEN and Stilla dPCR instruments
  • Multiplexing: analyze up to 4 different PICOglue Labels simultaneously

AMULATOR actome.de
  • Online analysis software
  • Personal cloud-based workspace
  • Free registration

  • Absolute quantification of targets
  • Direct graphical output of data
  • Basic statistical evaluation

PICO Products

Say bye to western blot and coIP and use our PICO Kits to detect your favourite protein in your lab.

Order in our webshop Contact us for a quote

PICO Services

We offer a comprehensive range of services to help you utilize the PICO technology. These services include the Antibody Quality Control to assess your own labeled antibodies, the hassle-free Antibody Labeling Service to conjugate antibodies of your choice with PICOglue labels, and the development of Custom PICO Assays tailored to your specific needs. Additionally we offer to label your antibodies with Custom DNA Labels.

PICO Antibody Quality Control Service PICO Antibody Labeling Service PICO Custom Assay Development Service Custom DNA Oligo Conjugation Service

Contact us!

Join us in advancing science and technology through Next Generation Discovery. Reach out to us today!

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